- Office of the Vice Chancellor
- Deputy Vice Chancellor Academics, Research and Student Affairs
- Deputy Vice Chancellor Administration Finance & Planning
- Registrar (Academic Affairs)
- Registrar Administration & Human Capital
- School of Education
- School of Business and Economics
- School of Humanities and Development Studies
- School of Science and Applied Technology
- Graduate School
- Laikipia University Institutional Scientific Ethics Review Committee (LU-ISERC)
- Directorate of Corporate Affairs
- Directorate of TVET, Career Placement, Alumni and External Linkages
- Directorate of Open, Distance, and e-Learning (ODeL)
- Directorate of Research, Human Rights & Gender
- Directorate of Planning Performance & Management
- Directorate of Examinations & Timetabling
- Directorate of Quality Assurance & Standards
- Directorate of Resource Mobilization and Investment
- Department of Biological and Biomedical Sciences and Technology
- Department of Chemistry and Biochemistry
- Department of Commerce
- Department of Computing and Informatics
- Department of Curriculum and Educational Management
- Department of Earth Sciences
- Department of Economics
- Department of Literary and Communication Studies
- Department of Mathematics
- Department of Psychology, Counselling and Educational Foundations
- Department of Social Studies
- Finance Department
- Internal Audit Department
- Legal Office
- Library Department
- Procurement Department
- Medical Department
- Student's Affairs Department
- Catering Department
- Security Department
- Estates Department
- Farm Department
- Halls Department
- Transport Department
