Dr. Isaac Njangiru Profile

   Name of Staff: Dr. Isaac Njangiru

   Designation/Rank: Senior Technologist I

   Laikipia University: School of Science & Applied Technology

   Email: injangiru@laikipia.ac.ke

        

 

Educational Background/Qualification

  • PhD (Anticancer drug development), University of Szeged, Hungary (2024)
  • Masters of Science in Medical Biochemistry, Kenyatta University, Kenya (2017)
  • Bachelors of Science in Biochemistry, Moi University, Kenya (2009)

Brief Auto-biography of the Faculty/Staff

Dr. Njangiru is an accomplished scientist specializing in anticancer drug development. He earned a PhD in Pharmaceutical Sciences (2024) from the University of Szeged, Hungary, where his research focused on novel approaches to combat cervical cancer. Dr. Njangiru holds a Master of Science in Medical Biochemistry (2017) from Kenyatta University, Kenya, and a Bachelor of Science in Biochemistry (2009) from Moi University. With a strong foundation in biochemistry and extensive expertise in medical research, he is passionate about advancing innovative therapies to improve global health outcomes. His academic journey reflects a commitment to excellence and a dedication to making meaningful contributions to the field of pharmaceutical sciences.

Research Interest

  1. Anticancer Drug Development
  2. Pharmacology and Toxicology
  3. Natural Products and Medicinal Chemistry
  4. Translational Research
  5. Nanomedicine in Oncology
  6. Molecular Biology and Genomics in Cancer

Publications

  1. Publications Kimani, N. L., Njangiru, I. K., Njagi, E. N. M., & Orinda, G. O. (2017). Antidiabetic Activity of Administration of Aqueous Extract of Berberis holstii. Journal of Diabetes Metabolism. doi: 10.4172/2155-6156.1000774
  2. Gitimu, R. M., Njangiru, I. K., & Njagi, E. N. M. (2017). Need for reference ranges for liver function tests in infants and children from Taita Taveta County, Kenya. Journal of Clinical Chemistry and Laboratory Medicine.
  3. Njangiru, I. K., Gitonga, N. Z., & Njagi, E. M. (2019). Hypoglycemic Potential and Safety of Aqueous Extract of Aspilia Mossambicensis in Alloxinised Diabetic Mice. Journal of Medical Research and Health Sciences. doi.org/10.15520/jmrhs.v2i3.38
  4. Tayeb, B. A., Njangiru, I. K., & Minorics, R. (2024). Beyond boundaries: Neuroprotective effects of steroids and ecdysteroids in SH‐SY5Y cells‐A systematic review. Neuroprotection. . doi.org/10.1002/nep3.37
  5. Njangiru, I. K. (2019). Bioscreening for Hypoglycemic Potential of Aqueous Extract of Tridax Procumbens in Mice Model. Journal of Medical Research and Health Sciences. doi.org/10.15520/jmrhs.v2i10.121
  6. Muhoro, A. M., Kosgei, J. J., Njangiru, I. K., Rasaki, L. A., & Farkas, E. É. (2024). Potential of Cladonia Foliacea Extract as an Oral Toxic Insecticide Against Adult Anopheles Gambiae, Malaria Vector in Western Kenya. Acta Botanica Hungarica. doi.org/10.1556/034.66.2024.3-4.7
  7. Tayeb, B. A., Osman, A. A., & Njangiru, I. K. (2024). Liquid biopsy biomarkers in breast cancer: An overview of systematic reviews. Clinica Chimica Acta. doi.org/10.1016/j.cca.2024.120063
  8. Njangiru, I. K., Bózsity-Faragó, N., Resch, V. E., Paragi, G., Frank, É., Balogh, G. T., ... & Minorics, R. (2024). A Novel 2-Methoxyestradiol Derivative: Disrupting Mitosis Inhibiting Cell Motility and Inducing Apoptosis in HeLa Cells In Vitro. Pharmaceutics. doi.org/10.3390/pharmaceutics16050622
  9. Le, T. M., Njangiru, I. K., Vincze, A., Zupkó, I., Balogh, G. T., & Szakonyi, Z. (2024). Synthesis and medicinal chemical characterisation of antiproliferative O, N-functionalised isopulegol derivatives. RSC advances. DOI: 10.1039/D4RA03467H
  10. Kimani, N. L., Njangiru, I. K., Njagi, E. N., & Orinda, G. O. (2017). Antidiabetic activity of administration of aqueous extract of Berberis holstii. doi: 10.4172/2155-6156.1000774.
  11. Njangiru, I. K., & Njeri, L. K. (2017). Effects of Oral Administration of Aqueous Extract of Tridax Procumbens on Body Organs and Hematological Parameters. International Journal of Contemporary Research and Review. doi.org/10.15520/ijcrr/2017/8/04/164.
  12. Muhoro, A. M., Ochomo, E. O., Kinyua, I. N., Kosgei, J. J., Rasaki, L. A., & Farkas, E. (2024). A study on the effectiveness of (+)-usnic acid as oral toxic sugar bait against adult male and female Anopheles gambiae. Malaria Journal. doi.org/10.1186/s12936-024-05141-4
  13. Molnár, B., Kinyua, N. I., Mótyán, G., Leits, P., Zupkó, I., Minorics, R., ... & Frank, É. (2022). Regioselective synthesis, physicochemical properties and anticancer activity of 2-aminomethylated estrone derivatives. The Journal of Steroid Biochemistry and Molecular Biology. doi.org/10.1016/j.jsbmb.2022.106064

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